Fructose receptor and fast grains (and maybe mycotoxins or heavy metals) switch us from fit to flabby
The gustatory receptor 43a (Gr43a) functions as a narrowly-tuned fructose receptor in taste neurons. Gr43a also functions as a fructose receptor in the brain.
The hormone leptin regulates appetite. When leptin rises, it signals fullness. Grains and refined sugar (especially fructose) cause leptin resistance. Similar calorie counts from fructose or glucose, fructose and protein, or fructose and fat, cause different metabolic effects.
Food companies have mastered the art of creating addictive foods through combining salt, fat, sugar and many proprietary flavorings.
Mycotoxins infect around 25% of the world’s grain, and response may seem typical, even generationally. Mycotoxins are not disabled during cooking or processing so they often make their way into final products.
Eating spices boosts resistance to toxins. Turmeric (curcumin), garlic and ellagic acid (in pomegranate) inhibit damage. Antioxidants may help reduce aflatoxin-induced mutagenicity and carcinogenicity. In the feed and food industry it is common to add binding agents like Montmorillonite or bentonite clay to affectively adsorb mycotoxins.
Bread made with ground grains and airborne microorganisms ferments more slowly and becomes more acidic removing more invisible lectins (which makes fatter babies and receptors less sensitive to insulin or leptin) while creating a final product that stays palatable longer.
Baker's yeast is a hybrid that is quick and convenient, although it produces bubbles very fast, more lectins remain and there is a shorter shelf-life to the leavened product.
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